Monday, October 20, 2008

Molecular Biology Applications for the Pharmaceutical and Biotechnology

The investments and economic output of all of these types of applied biotechnologies form what has been described as the bioeconomy.Bioinformatics is an interdisciplinary field which addresses biological problems using computational techniques and makes the rapid organization and analysis of biological data possible. The field may also be referred to as computational biology and can be defined as conceptualizing biology in terms of molecules and then applying informatics techniques to understand and organize the information associated with these molecules on a large scale.

Bioinformatics plays a key role in various areas such as functional genomics structural genomics and proteomics and forms a key component in the biotechnology and pharmaceutical sector.Pharmacogenomics is the study of how the genetic inheritance of an individual affects hisher bodys response to drugs.Pharmaceuticals Incorporated is a global biotechnology company committed to the discovery and development of breakthrough small molecule drugs for serious diseases. The Company?s strategy is to commercialize its products both independently and in collaboration with major pharmaceutical companies.

It is a coined word derived from the world pharmacology and genomics. It is hence the study of the relationship between pharmaceuticals and genetics. The vision of pharmacogenomics is to be able to design and produce drugs that are adapted to each persons genetic makeup.. Development of tailormade medicines. Using pharmacogenomics pharmaceutical companies can create drugs based on the proteins enzymes and RNA molecules that are associated with specific genes and diseases.

These tailormade drugs promise not only to maximize therapeutic effects but also to decrease damage to nearby healthy cells.. More accurate methods of determining appropriate drug dosages. Knowing a patient genetics will enable doctors to determine how well his her body can process and metabolize a medicine. This will maximize the value of the medicine and decrease the likelihood of overdose.

Human genetics is the foundation of disease as well as the response to pharmaceutical agents. Today, promising drugs are abandoned due to the lack of significant efficacy in broad patient populations. Recently, blockbuster drugs have been removed from the market due to unexplained toxicity not revealed in clinical trials. A need exists to economically address individual human variation in disease and drug response. With the latest DNA sequencing technologies ushering in an era of personalised medicine the application of these technologies could provide the flexible genetic tools needed to support the drug discovery and development process.